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When Tripp Campbell wins a radio contest to meet his favorite band, Iron Weasel, he lands a spot as their new guitar player. Unfortunately, things take an unexpected turn when the band moves into Tripp's house.
Tripp gets dumped by Lana, the prettiest girl in his class so he's inspired to write a new song, "I Wanna Punch Stuff." Meanwhile, Tripp surprises his band mates with a visit from professional mixed martial arts fighter and former roadie, Ernesto the Besto, who unbeknownst to Tripp, has a bone to pick with Iron Weasel.
A problem arises for Iron Weasel when their new move, the "Weasel Slap", is uploaded on video by Tripp. With this, Iron Weasel's reputation is compromised when a fan gets injured while performing the new move.
When Tripp finds out that Arelene, an annoying classmate, has a record producer for a father, he takes her out on a date in order to help out the band. However, a new Iron Weasel demo called "Annoying Arlene" accidentally falls into her hands. It's now up to the guys to get the CD back before anyone hears it.
Iron Weasel and Tripp decide to film a music video. However, things get out of hand when they choose Tripp's school as the place to film it at. Being called an idiot for the last time, Ash decides to quit the band and becomes the new high school janitor.
Arlene invites Tripp and Iron Weasel to her house. However, they look at this as an opportunity to impress Arlene's record-producing father.
Iron Weasel enters a televised rock off in order to "out rock" the reigning champions.
It's Tripp's birthday, but things get crazy when his mom and Iron Weasel both throw him a party on the same day.
Iron Weasel decide to record a charity single for Tripp's grandmother's retirement home. But when the band purposely spends the money from the song on a sky-diving trip, They must perform community service to pay off their debt to the home.
Tripp gets Iron Weasel parts in a horror film called "Spiders, Snakes, and Clowns". Unfortunately, the band is too scared to be a part of it, Burger being afraid of spiders, Derek being afraid of snakes, and Ash being afraid of clowns. Izzy tries to convince the director to let her be the part of the film.
Ash gets stuck in a pickle costume; Burger's hand gets caught in a vase; Derrick helps Iron Weasel's biggest fan.
Tripp unintentionally breaks Derek's motorcycle on the same night Iron Weasel's former manager comes to dinner to put them back on top.
Tripp is able to get Iron Weasel a concert tour, but unfortunately for them things get crazy.
Iron Weasel goes too far with "Prank Week" and embarrasses Tripp in front of the whole school.
Tripp gets back with Lana and encourages her to be less materialistic. But with Lana's new attitude means that she will not splurge money unnecessarily, that includes not hiring Iron Weasel for her birthday party and multiple monthly parties. Derek, Burger and Ash come up with a plan to try to change her attitude by throwing a party for Izzy to make Lana jealous.
Iron Weasel's former guitarist "Bleed" comes back to try and get back in the band by taking Tripp's spot.
Cole and Dylan Sprouse from "The Suite Life On Deck" guest star on an episode of "I'm In The Band". Iron Weasal get to preform on the S.S. Tipton.
Izzy's dreams come true when one of the band members looses their voice and she fills in.
Career day is coming up and Beth and Izzy are excited. But, Tripp isn't. Also, the magazine Cool Awesome wow gets a new Cover
Tripps books an interview for the band. But, a detention stands in the way. Meanwhile, Beth takes a self defence class
The band creates a reality show but soon they find it is a lot of work.